Folks, if you’re glued to the markets like I am, you’ve probably already spotted Leap Therapeutics (LPTX) lighting up your screen this morning. As of this writing, early in the trading session on October 6, 2025, the stock’s popped more than 76% in pre-market action, turning heads and sparking chatter across trading floors and chat rooms alike. That’s the kind of move that gets your heart racing – a biotech darling suddenly flirting with the wild world of digital assets, courtesy of none other than the Winklevoss twins. Yeah, those guys from the crypto frontier. But hold your horses; this isn’t just hype. It’s a real pivot that’s got investors buzzing about fresh funding and big-picture strategy. Let’s break it down, because in this market, understanding the why behind the whoosh is half the battle.

The Big News That’s Fueling the Fire

Picture this: A scrappy biotech company, knee-deep in cancer-fighting drugs, announces it’s pulling in nearly $59 million from a private stock sale – led by Winklevoss Capital, the firm run by Cameron and Tyler Winklevoss. That’s right, the duo who’s been knee-deep in Bitcoin since the early days is now teaming up with Leap to kick off a “digital asset treasury strategy.” In plain English? They’re injecting cash to let Leap dip its toes into cryptocurrencies and other digital goodies, aiming to build long-term value for shareholders while keeping the lights on for their drug development.

The deal’s structured as a private investment in public equity – or PIPE, for short – selling about 95.8 million shares (or pre-funded warrants in place of some) plus warrants for another 71.9 million shares at a strike price around 53 cents each. Closing’s slated for around October 8, assuming all the paperwork checks out. And get this: As part of the package, Winklevoss gets to nominate two board seats, including the chair. That’s not just money; that’s muscle – strategic know-how from folks who’ve navigated crypto’s ups and downs like pros.

A chunk of that cash? It’ll fuel Leap’s ongoing work on their promising therapies, like sirexatamab and FL-501. Speaking of which, timing couldn’t be better: Leap’s gearing up to unveil final data from a key Phase 2 trial of sirexatamab in colorectal cancer patients at the European Society for Medical Oncology Congress on October 19 in Berlin. If that data shines – and early peeks have been encouraging – it could be another rocket booster for the stock.

Who Is Leap Therapeutics, Anyway?

Leap’s no newbie in the biotech game. They’re all about crafting targeted treatments and immune-boosting therapies to tackle tough cancers, like those in the stomach, gynecologic areas, and colon. Their star player is sirexatamab (once called DKN-01), an antibody that zeroes in on a protein called Dickkopf-1, which helps tumors hide from the body’s defenses. They’ve been testing it in combo with other drugs for esophagogastric and colorectal cancers, and the results so far? Promising enough to keep the pipeline humming.

Then there’s FL-501, still in the early lab stages, targeting a protein called GDF-15 that’s linked to cancer growth and even some nasty side effects from treatments. And don’t forget FL-301, another antibody in the works for gastric and pancreatic cancers by hitting Claudin18.2. It’s classic biotech: High-stakes science with the potential to change lives, but it takes serious dough to get from lab bench to medicine cabinet.

Lately, though, Leap’s been playing defense. Back in August, they reported a second-quarter net loss of $16.6 million – better than the $20.4 million hit the year before, thanks to slashing research costs by over 40% and trimming general expenses. But cash was dwindling fast: Down to $18.1 million by June 30 from $47.2 million at year’s end, burned mostly on trials and operations. They even cut their workforce by 75% to stretch that runway, and the board’s been shopping around for partnerships or even a sale to maximize value. Enter the Winklevoss lifeline – not just a bailout, but a bold swing at blending biotech brains with blockchain bucks.

Why This Could Be a Game-Changer (And Why It’s Risky Business)

Let’s talk upside first, because that’s what has traders salivating. This infusion gives Leap breathing room to push sirexatamab through more trials without the constant scramble for funds. Pair that with Winklevoss’s crypto smarts, and you’ve got a company experimenting with holding digital assets on the balance sheet – think Bitcoin or Ethereum as a hedge against inflation or a growth play. In a world where even big corps like MicroStrategy are stacking sats, why not a biotech? It could juice returns if the market stays hot, and that board shake-up brings fresh eyes to strategy.

But hey, let’s keep it real – this market’s a rollercoaster, and biotechs like Leap ride the front car. The PIPE means dilution: All those new shares could water down existing holders’ stakes if exercised. Crypto? Volatile as all get-out – one bad headline, and poof, treasury value tanks. Plus, drug development’s a crapshoot; trials flop, regulators drag feet, and suddenly you’re back to square one. Leap’s stock’s been a wild ride, down over 25% just on October 3 before this pop. The benefits scream potential – innovative funding, pipeline progress – but the risks? They’re as real as that knot in your stomach during a market dip.

A Quick Trading Lesson from Today’s Action

This Leap saga’s a textbook case of how news can flip a stock overnight. Biotech announcements like PIPE deals or trial data drops are pure adrenaline – they signal survival and growth, drawing in momentum chasers. But the key? Don’t chase the spike blind. Dig into the details: Who’s investing? What’s the cash for? How’s it fit the bigger picture? Markets reward the prepared, not the panicked. Stay tuned to earnings, press releases, and those conference spotlights – they’re your edge in spotting the next mover before the herd stampedes in.

In the end, plays like LPTX remind us why we love this game: Breakthroughs born from brainpower and a bit of bravado. Whether you’re a seasoned trader or just dipping in, keeping your finger on the pulse is everything.Want to catch these market jolts as they happen? Join thousands of smart traders getting free daily alerts straight to your phone – no fluff, just the tips to help you navigate the chaos. Tap here to sign up. It’s your ticket to trading smarter, every day. What’s your take on Leap’s crypto leap? Sound off below – let’s chat!

Author:
Jeff Williams

Jeff Williams is a full-time day trader with over 15 years experience. Thousands of entry-level and experienced traders alike – day-traders and swing-trade small cap stock traders – credit Jeff with guiding them to turning small accounts into big accounts.

Jeff’s "Small Account Challenge" shows people how to transform accounts from a few thousand dollars into $25k, $50k or even $100k.

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